BPC-157
$70.00
This research only product is supplied in a 3ml vial containing 10mg of BPC-157 as a lyophilized powder. Every compound undergoes stringent independent 3rd party testing in a US laboratory with verified 99%+ purity and QR link to the COA stamped on the vial.
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For Research Purposes Only. This product is not intended for human consumption. By purchasing, you confirm that you are a qualified researcher and will use this product in compliance with all applicable laws and regulations.
Description
BPC-157, a synthetic pentadecapeptide derived from human gastric juice, promotes healing through multiple interconnected mechanisms, primarily by stimulating angiogenesis, modulating nitric oxide pathways, enhancing growth factor signaling, and upregulating genes involved in tissue repair and anti-inflammation.
Mechanisms of Action
- •Angiogenesis and Vascular Effects: Binds to VEGFR2 receptors on endothelial cells, triggering the Akt-eNOS pathway to boost nitric oxide production, dilate blood vessels, and enhance circulation and new vessel formation to injured areas.
- •Nitric Oxide Modulation: By upregulating Nos3 (eNOS) and Nos1 while suppressing Nos2 (iNOS), BPC-157 improves endothelial function, counteracts ischemia/reperfusion injury, and promotes reperfusion in damaged tissues.
- •Growth Hormone and Cellular Signaling: Increases growth hormone receptor expression in tendon fibroblasts, potentiating cell proliferation via JAK-2 activation. Also activates FAK-paxillin complexes for cell migration during wound healing.
- •Gene Expression and Repair: Upregulates genes like Egr1 and Vegfr2 for vascularization, speeds cellular regeneration, and supports anti-inflammatory effects.
- •Antioxidant and Protective Roles: Its structure (four carboxylic groups) enables reactive oxygen species scavenging, maintaining vascular integrity and reversing injurious cycles.
Tissue-Specific Effects
- •Musculoskeletal: Joints, ligaments, tendons, muscles, and fractures via upregulated cell growth, proliferation, survival, and angiogenesis.
- •Gut and CNS: Cytoprotection, mucosal integrity, and recovery from reperfusion disturbances.
Technical Data
- Form: Lyophilized powder
- Molecular Formula: C₆₂H₉₈N₁₆O₂₂
- Storage: Protect from light and moisture, keep tightly sealed, refrigerate reconstituted solution